Honest and straightforward small-town Shirlee Kenyon chucks her boyfriend and heads for Chicago. Accidentally having to host a radio problem phone-in show, it is clear she is a natural and is hired on the spot. But the station insists she call herself Doctor, and as her popularity grows a local reporter starts digging for the truth. Problem is, the more he is around her the more he fancies her.

Alan Johnson has everything he needs to get through life: a good job, a beautiful and loving wife, and their wonderful children. Yet he feels isolated because he finds having a hard-working job and managing a family too much to handle and has no one to talk to about it. Charlie Fineman, on the other hand, doesn't have a job or a family. He used to have both until a terrible loss, and the grief caused him to quit his job and isolate himself from everyone around him. As it turns out, Alan and Charlie were roommates in college, and a chance encounter one night rekindles the friendship they shared. But when Charlie's problems become too much to deal with, Alan is determined to help Charlie come out of his emotional abyss.

Grief, recovery, and human contact. Brian is a great guy - a sweet father, a good husband, and a loyal friend to his boyhood pal Jerry who's a junkie. When tragedy strikes, Jerry tries to help Brian's wife and children cope, and Audrey, Brian's widow, tries to help Jerry kick the habit. Loss and addiction are stubborn. The story starts on the day of the funeral, with Brian appearing in flashbacks. A neighbor's divorce, a dinner party that includes a young woman from the Narcotics Anonymous group Jerry attends, and thinking back to a fire in Brian and Audrey's garage give the story texture.